Literature on Caries Risk and Cancer Therapies
Management of patients who have undergone head and neck cancer therapy (abstract)
Fischer and Epstein
2008, Dental Clinics of North America
Dental professionals should provide preventive and supportive care, including education and symptom management, for patients experiencing oral complications related to cancer therapy, and should closely monitor patients' level of distress, ability to cope, and treatment response.
Managing complications of radiation therapy in head and neck cancer patients: Part II: Management of radiation-induced caries (abstract)
Chai et al.
2006, Singapore Dental Journal

In this article, the management of dental caries, a sequalae of xerostomia following radiation therapy is reviewed.
Dental management of chemoradiationpatients (abstract)
Chung and Sung
2006, Journal of the California Dental Association
The purpose of this article is to review the different radiation and chemotherapy regimens used to treat patients with head and neck cancers, as well as protocols in the dental management of these patients before, during, and after medical treatment.
Clinical evaluation of the intraoral fluoride releasing system in radiation-induced xerostomic subjects. Part I: Fluorides (abstract)
Chambers et al.
2006, Oral Oncology
Radiation-induced xerostomia results in significant changes in the oral cavity particularly oral microbial changes, which include a marked increase in the number of cariogenic organisms, notably Streptococcus mutans and lactobacillus species. This loss of the capacity to secrete saliva creates or promotes the rapid onset and progression of rampant dental caries.
Radiation-related damage to dentition (abstract)
Kielbassa et al.
2006, The Lancet Oncology
This Review focuses on the multifactorial causes of so-called radiation caries and presents possible treatment strategies to avoid loss of dentition.
Evaluation, prevention and management of radiotherapy-induced xerostomia in head and neck cancer patients (abstract)
de Castro and Federico
2006, Current Opinion in Oncology
As part of the multidisciplinary approach to head and neck cancer patients, radiation therapy plays an essential role, improving locoregional control. Radiation therapy-induced xerostomia is a late side-effect that increases the risk for developing dental caries and compromises oral mucosal integrity, resulting in oral pain, loss of taste, difficulties with swallowing and chewing, sleep disorders and worse quality of life. This review focuses on evaluation, prevention and management of radiation therapy-induced xerostomia.
Prevention and treatment of the consequences of head and neck radiotherapy (abstract)
Vissink et al.
2003, Critical Reviews of Oral Biology & Medicine
In this review, the various possibilities for prevention and/or treatment of radiation-induced changes in healthy oral tissues and their consequences are discussed.
Manifestations and treatment of xerostomia and associated oral effects secondary to head and neck radiation therapy (abstract)
Garg and Malo
1997, Journal of the American Dental Association
For patients with severe, chronic xerostomia who have some residual salivary tissue, the use of a sialagogue can promote an increased flow of saliva and treat the symptoms.