Indiana University Oral Health Research Institute



Long regarded by academic peers and industry as a leading center for preventive dentistry research, the Oral Health Research Institute has served as Indiana University School of Dentistry's core research facility for over four decades. OHRI clinical and laboratory research facilities support a wide range of studies including, caries and erosion preventive agents, anti-plaque and anti-gingivitis agents, anti-calculus agents, stain prevention and removal agents, and whitening/bleaching agents.  Beginning with stannous fluoride toothpaste, the first clinically proven decay preventive formula,  OHRI has an impressive portfolio of clinical trials and testing capabilities that has contributed significantly to dental health in the U.S. and abroad. This self supporting institute was created without government funding and has a distinguished reputation for its top-notch performance as a testing center for a wide variety of dental products. OHRI employs over 70 full-time faculty and staff members which can be increased with additional temporary employees,  depending on the needs of each study.

As a unique extension of Indiana University School of Dentistry's research capabilities, supported by the faculty of the Department of Preventive and Community Dentistry, OHRI can meet investigator's research and testing challenges by offering the following test-site advantages:

  • Leader in dental research since early 1970's
  • Reliable laboratory and bioresearch models that have significant relevance to the oral environment
  • Site of clinical trials of the first fluoride-containing dentifrice and effective tartar control dentifrice systems
  • Pioneers in the development of controlled clinical studies relating to the performance of restorative materials in the oral cavity and testing of tooth whitening agents
  • Access to a large patient population of suitable project subjects (IUSD developed patient pool of over 45,000 individuals)
  • Convenient midwestern location at the "Crossroads of America"