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Capabilities

DENTAL CARIES

We specialize in the use of the In situ Caries models. We can design and perform studies using fluoride dose-response controls, which is considered to be the gold standard for evaluating the efficacy of new fluoride dentifrice products, oral rinses and other fluoride delivery systems. Our studies are characterized by having large subject panels and the capability of sustaining complex designs. We have an established panel of lower partial denture wearers that have been preselected to fulfill the needs of these studies. Our site also has experience with clinical studies on fluoride pharmacokinetics.

Short-term In situ Remineralization Model

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Longer-term In situ Demin/Remin Model

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In Situ Biofilm Model

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EARLY CARIES DETECTION

We have experience in early caries detection studies utilizing highly trained and calibrated ICDAS examiners. We are also experienced and equipped with other early caries detection systems such as the QLF-D (Quantitative Light-induced Fluorescence-digital), Canary and DIAGNOdent.

QLF-D (Quantitative Light-induced Fluorescence-digital)

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                                  Canary System
                  

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                                                                                                                                                                      DIAGNOdent               

 

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DENTAL EROSION

We also specialize in conducting clinical studies with In situ Erosion models which involve the use of custom made palatal appliances holding enamel specimens to model aspects of the demineralization/remineralization process. We have an established panel of subjects with previously made appliances to meet the needs of these studies.

Short-term In situ Erosion DEMIN Model

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Short-term In situ Erosion REMIN Model

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In situ Long-term EROSION / ABRASION Model 

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Dry Mouth and Sjögren’s Syndrome

We have experience in dry mouth and Sjögren’s syndrome studies testing both over-the-counter products for symptom relief and investigational drugs that may lead to overall improvement of signs and symptoms. 

GINGIVITIS AND PERIODONTAL DISEASE

We perform gingivitis and periodontal studies that may include radiographic digital imaging, dental prophylaxis, scaling and root planing, supra and subgingival plaque sampling, and product applications. Our clinic offers very sensitive testing instruments for periodontal disease diagnosis including the Periotron 8000, and the Florida Periodontal probe system. Our dental examiners are proficient and calibrated in periodontal diagnostic indexes such as the Turesky plaque index, Silness and Loe gingivitis index, Bleeding upon Probing and periodontal probing measurements.

DENTURE ADHESIVES

We are experienced in conducting denture adhesive studies utilizing trained and calibrated personnel. We have an established panel of upper denture wearing subjects. Our facility offers a large room with portable lounge chairs, tables and a refrigerator. This allows subjects a comfortable space for studies that require them to stay for extended periods of time.