Dr. Marco C. Bottino, DDS, MSc, PhD

Dr. Marco C. Bottino, DDS, MSc, PhD
Dr. Marco C. Bottino, DDS, MSc, PhD

Associate Professor and Dental Material Graduate Program Director
Department of Biomedical and Applied Sciences

Contact Info

Phone  (317) 274-3725
Fax       (317) 278-7462

Office Address

Indiana University School of Dentistry
1121 W. Michigan St. Rm. DS112
Indianapolis, IN. 46202


D.D.S., Paulista University, São Paulo, Brazil

M.Sc., Nuclear Technology (Materials), Institute for Energy & Nuclear Research, University of São Paulo, São Paulo, Brazil

Ph.D., Materials Science, Department of Materials Science Engineering, University of Alabama at Birmingham, Birmingham, AL

Research Interests

  • Periodontal regeneration
  • Scaffolds for tissue engineering
  • Cell-biomaterial response and in vivo studies
  • Dental biomaterials (Metals, Ceramics, Polymers, and Composites)
  • Development of novel light curing dental composites



Papers Published in Refereed Journals

Bottino, M.C.; Valandro, L.F.; Özcan M.; Amaral R.; Bottino M.A.; Ussui V.; Bressiani, A.H.A.; Lazar, D.R.R. Adhesive Durability of Phosphate Monomer Resin Cement to an Experimental Y-TZP Ceramic obtained via Coprecipitation. Journal of Biomedical Materials Research Part B: Applied Biomaterials (in preparation).

Bottino, M.C.; Thomas, V; Janowski, G.M. A Novel Spatially Designed and Functionally Graded Electrospun Membrane for Periodontal Regeneration. Acta Biomaterialia (In press).

Bottino, M.C.; Thomas, V; Jose, M.V.; Dean, D.R.; Janowski, G.M. Enhancement of AlloDerm Properties via Natural Cross-linking. Journal of Biomedical Materials Research Part B: Applied Biomaterials (In press).

Bottino, M.C.; Jose, M.V.; Thomas, V.; Dean, D.R.; Janowski, G.M. Freeze-Dried Acellular Dermal Matrix Graft: Effects of Rehydration on Physical, Chemical, and Mechanical Properties. Dental Materials, 2009:25(9):1109-15.

Tortamano A.; Lenzi, D.C.; Haddad, A.C.S.S.; Bottino, M.C.; Dominguez, G.C.; Vigorito, J.W. Low-level Laser Therapy for Pain Caused by Placement of the First Orthodontic Archwire: A Randomized Clinical Trial. American Journal of Orthodontics and Dentofacial Orthopedics, 2009:136(5):662-7.

Bottino, M.C.; Coelho, P.G.; Henriques, V.A.R.; Higa, O.Z.; Bressiani, A.H.A.; Bressiani, J.C. Processing, Characterization, and In Vitro/In Vivo Evaluations of Powder Metallurgy Processed Ti-13Nb-13Zr Alloys. Journal of Biomedical Materials Research Part A, 2009:88(3):689-96.

Lazar, D.R.R.; Bottino, M.C.; Özcan, M.; Valandro, L.F.; Amaral, R.; Ussui, V.; Bressiani, A.H.A. Y-TZP ceramic processing from coprecipitated powders: A Comparative Study with three Commercial Dental Ceramics. Dental Materials, 2008:24(12):1676-85.

Muller, F.A.; Bottino, M.C.; Muller, L.; Henriques, V.A.R.; Lohbauer, U.; Bressiani, A.H.A.; Bressiani, J.C. In Vitro Apatite Formation on Chemically Treated (P/M) Ti-13Nb-13Zr. Dental Materials, 2008:24(1):50-56.

Bottino, M.C.; Coelho, P.G.; Yoshimoto, M.; Konig Jr., B.; Henriques, V.A.R.; Bressiani, A.H.A.; Bressiani, J.C. Histomorphologic Evaluation of Ti-13Nb-13Zr Alloys Processed via Powder Metallurgy: A Study in Rabbits. Materials Science & Engineering C, 2008:28(2):223-227.

Bottino, M.C.; Özcan, M.; Coelho, P.G.; Valandro, L.F.; Bressiani, J.C.; Bressiani, A.H.A. Micro-morphological Changes Prior to Adhesive Bonding: High-alumina and Glassy-matrix Ceramics. Brazilian Oral Research, 2008:22(2):158-63.

Taddei, E.B.; Henriques, V.A.R.; Silva, C.R.M.; Cairo, C.A.A.; Bottino, M.C. Cytotoxicity and Influence of Solution Treatment on Microstructure of a Ti-35Nb-7Zr-5Ta Alloy for Use in Orthopedics Prosthesis. Revista Matéria (UFRJ), 2007:12:120-127.

Rigo, E.C.S.; Bottino, M.C.; Carraro, B.D.; Taddei, E.B.; Henriques, V.A.R.; Silva, C.R.M.; Bressiani, A.H.A.; Bressiani, J.C. Biomimetic Coatings on Ti-based Alloys Obtained by Powder Metallurgy for Biomedical applications. Materials Science Forum, 2006:530-531:599-604.

Bottino, M.C.; Oyafuso, D.K.; Coelho, P.G.; Taddei, E.B.; Henriques, V.A.R.; Bottino, M.A.; Bressiani, J.C. Ceramic Bonding to Biocompatible Titanium Alloys Obtained by Powder Metallurgy. Materials Science Forum, 2006:530-531:605-611.

Valandro, L.F.; Özcan, M.; Bottino, M.C.; Scotti, R.; Bottino, M.A.; Della Bona A. Bond Strength of a Resin Cement to High-alumina and Zirconia-reinforced ceramics: The Effect of Surface Conditioning. J Adhesive Dentistry, 2006:8:175-81.

Bottino, M.C.; Valandro, L.F.; Kantorski, K.Z.; Bressiani, J.C.; Bottino, M.A. Polishing Methods of an Alumina Reinforced Feldspar Ceramic. Brazilian Dental Journal, 2006:17:285-289.

Bottino, M.C.; Lázaro Filho, M.; Tortamano, P.; Valandro, L.F. Fiber Posts: The State of the Art. Jornal Brasileiro de Clínica e Estética em Odontologia, 2006:5:14-23 (in Portuguese).

Bottino, M.C.; Valandro, L.F.; Tortamano, P.; Tortamano, I. Peri-implantitis: A Therapeutic Management. JBC. Jornal Brasileiro de Clínica Odontológica Integrada, 2005:9:66-72 (in Portuguese).

Valandro, L.F.; Bottino, M.C.; Kantorski, K.Z.; Bottino, M.A. Fiber Posts with Adhesive Systems: An Aesthetic Alternative that Also Preserves Dental Structures. Endodontic Therapy, 2005:5:A-D.

Bottino, M.C.; Benetti, A.R.; Miranda, C.B.; Pagani, C. A Comparison of LED Polymerization Effectiveness to Conventional and Soft-start Techniques. Journal of Institute of Health Science, 2003:21(1):91-96.

Pagani, C.; Miranda, C.B.; Bottino, M.C. Relative Fracture Toughness of Different Dental Ceramics. Journal of Applied Oral Science, 2003:11:69-75.

Miranda, C.B.; Pagani, C.; Bottino, M.C.; Benetti, A.R. A Comparison of Microhardness of Indirect Composite Restorative Materials. Journal of Applied Oral Science, 2003:11:157-161.

Bottino, M.C.; Giannini, V.; Bottino, M.A. In Vitro Evaluation by Using the Liquid Penetrant Method Between a Titanium Alloy (Reintitan Ti1/Dentaurum) and two Aesthetic Systems: Artglass and Targis. Revista Brasileira de Prótese Clínica e Laboratorial, 2002:4:234-240 (in Portuguese).